Anti-Adalimumab polyclonal antibody
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More Files
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Enzyme-linked Immunoabsorbent Assay
Anti-Adalimumab polyclonal antibody (Cat # PAB31791) binds with Adalimumab. Coating antigen: Adalimumab, 1 ug/mL. Anti-Adalimumab polyclonal antibody (Cat # PAB31791) dilution start from 1000 ng/mL. EC50 = 5.474 ng/mL.
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Specifications
Product Description
Rabbit polyclonal antibody raised against Adalimumab.
Target gene is TNF alpha.Immunogen
Adalimumab.
Host
Rabbit
Specificity
The product is specific for Adalimumab. This antibody serves as an excellent positive control for Adalimumab immunogenicity (ADA) assays.
Form
Lyophilized
Preparation Method
This antibody is produced from sera of a rabbit immunized with Adalimumab.
Purification
Antigen affinity purification
Recommend Usage
ELISA (ELISA detection: 0.05-0.2 ug/mL) (Direct ELISA)
Immunogenicity assay
The optimal working dilution should be determined by the end user.Inhibitory IC50
N/A
Storage Buffer
Lyophilized from PBS, pH 7.4 (0.02% sodium azide).
Storage Instruction
Store at -20°C on dry atmosphere, lyophilized antibodies are stable at 1 years.
After reconstitution with deionized water (or equivalent) to a final concentration of 0.5 mg/mL, it can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C or below.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
Anti-Adalimumab polyclonal antibody (Cat # PAB31791) binds with Adalimumab. Coating antigen: Adalimumab, 1 ug/mL. Anti-Adalimumab polyclonal antibody (Cat # PAB31791) dilution start from 1000 ng/mL. EC50 = 5.474 ng/mL.Immunogenicity assay
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Gene Info — TNF
Entrez GeneID
7124Gene Name
TNF
Gene Alias
DIF, TNF-alpha, TNFA, TNFSF2
Gene Description
tumor necrosis factor (TNF superfamily, member 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
Other Designations
APC1 protein|OTTHUMP00000029281|OTTHUMP00000037669|TNF superfamily, member 2|TNF, macrophage-derived|TNF, monocyte-derived|cachectin|tumor necrosis factor alpha
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Interactomes
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Pathways
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Diseases
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