In Situ Hybridization (ISH) encompasses the use of CISH (Chromogenic In Situ Hybridization), traditional FISH (Fluorescence In Situ Hybridization) probes, and new generation of mutaFISH™ (mutation-specific FISH) probes and RollFISH (Rolling FISH) probes for the detection of chromosome aneuploidy and split, DNA gene amplification and translocation, mRNA single nucleotide variant, splice variant, and wild type, and miRNA in cells and tissues. Customers can provide their probes of interest or choose from Abnova’s large catalogue collection of ready-to-go CISH, FISH, mutaFISH™, and RollFISH probes. New probes can also be designed and produced for the customers upon request.

See Technologies: FISH, mutaFISH™

Advantages

  • Identify DNA and RNA variants
  • Provide guidance on probe selection
  • Select suitable cell and tissue samples
  • Define applications, sensitivity, and specificity
  • Fast turnaround time for results
 
 

Summary of Molecular Targets, Probe Selection, and Intended Samples

    CISH FISH mutaFISH™ RollFISH
DNA Chromosome Aneuploidy FFPE Tissue Cell
Frozen Tissue
FFPE Tissue
Cell  
Chromosome
Split
FFPE Tissue Cell
Frozen Tissue
FFPE Tissue
   
Gene
Amplification
FFPE Tissue Cell
Frozen Tissue
FFPE Tissue
Cell  
Gene Translocation   Cell
Frozen Tissue
FFPE Tissue
   
mRNA Single
Nucleotide
Variant
    Cell
Frozen Tissue
FFPE Tissue
 
Splice
Variant
    Cell
Frozen Tissue
 
Wild Type     Cell
Frozen Tissue
FFPE Tissue
FFPE Tissue
miRNA    Cell
Frozen Tissue
FFPE Tissue
 Cell
Frozen Tissue
FFPE Tissue
   

 

For any inquiry, please contact : OEM@abnova.com