In Situ Hybridization (ISH) encompasses the use of CISH (Chromogenic In Situ Hybridization), traditional FISH (Fluorescence In Situ Hybridization) probes, and a new generation of mutaFISH™ (mutation-specific FISH) probes and RollFISH (Rolling FISH) probes for the detection of chromosome aneuploidy and split, DNA gene amplification and translocation, mRNA single nucleotide variant, splice variant, and wild type, and miRNA in cells and tissues. Customers can provide their probes of interest or choose from Abnova’s large catalog collection of ready-to-go CISH, FISH, mutaFISH™, and RollFISH probes. New probes can also be designed and produced for the customers upon request.

See Technologies: FISH, mutaFISH™

Advantages

  • Identify DNA and RNA variants
  • Provide guidance on probe selection
  • Select suitable cell and tissue samples
  • Define applications, sensitivity, and specificity
  • Fast turnaround time for results
 
 

Summary of Molecular Targets, Probe Selection, and Intended Samples

 

CISH

FISH

mutaFISH™

RollFISH

DNA

   

Chromosome

Aneuploidy

FFPE Tissue

Cell
Frozen Tissue
FFPE Tissue
Cell  

Chromosome

Split

FFPE Tissue

Cell
Frozen Tissue
FFPE Tissue
   

Gene

Amplification

FFPE Tissue

Cell
Frozen Tissue
FFPE Tissue
Cell  

Gene Translocation

  Cell
Frozen Tissue
FFPE Tissue
   
mRNA

 Single

Nucleotide
Variant

     Cell
Frozen Tissue
 

Splice
Variant

    Cell
Frozen Tissue
FFPE Tissue
FFPE Tissue

Wild Type

     Cell
Frozen Tissue
FFPE Tissue
 
miRNA   Cell
Frozen Tissue
FFPE Tissue
Cell
Frozen Tissue
FFPE Tissue
   
 

 

 

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