PCNA polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of PCNA.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PCNA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
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Gene Info — PCNA
Entrez GeneID
5111Gene Name
PCNA
Gene Alias
MGC8367
Gene Description
proliferating cell nuclear antigen
Omim ID
176740Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
Other Designations
DNA polymerase delta auxiliary protein|OTTHUMP00000030189|OTTHUMP00000030190|cyclin
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney.
Vogetseder A, Palan T, Bacic D, Kaissling B, Le Hir M.
American Journal of Physiology. Cell Physiology 2006 Sep; 292(2):C807.
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Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney.
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