CBL monoclonal antibody (M01A), clone 6D12

Catalog # H00000867-M01A

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Size:200 uL
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

CBL monoclonal antibody (M01A), clone 6D12 Western Blot analysis of CBL expression in K-562 ( Cat # L009V1 ).

Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of CBL expression in transfected 293T cell line by CBL monoclonal antibody (M01A), clone 6D12.

Lane 1: CBL transfected lysate (Predicted MW: 99.6 KDa).
Lane 2: Non-transfected lysate.

QC Test

Western Blot detection against Immunogen (36.74 KDa) .

  • Specifications

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant CBL.

    Immunogen

    CBL (NP_005179, 736 a.a. ~ 835 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSER

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (36.74 KDa) .

    Storage Buffer

    In ascites fluid

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Cell lysate)

    CBL monoclonal antibody (M01A), clone 6D12 Western Blot analysis of CBL expression in K-562 ( Cat # L009V1 ).

    Western Blot (Transfected lysate)

    Western Blot analysis of CBL expression in transfected 293T cell line by CBL monoclonal antibody (M01A), clone 6D12.

    Lane 1: CBL transfected lysate (Predicted MW: 99.6 KDa).
    Lane 2: Non-transfected lysate.

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — CBL

    Entrez GeneID

    867

    GeneBank Accession#

    NM_005188

    Protein Accession#

    NP_005179

    Gene Name

    CBL

    Gene Alias

    C-CBL, CBL2, RNF55

    Gene Description

    Cas-Br-M (murine) ecotropic retroviral transforming sequence

    Omim ID

    165360

    Gene Ontology

    Hyperlink

    Gene Summary

    The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

    Other Designations

    oncogene CBL2

  • Interactomes
  • Pathways
  • Diseases
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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