CREB1 recombinant monoclonal antibody, clone 21E3
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562 whole cell lysate; Lane 2: THP-1 whole cell lysate; Lane 3: Mouse brain tissue lysate; Lane 4: Rat brain tissue lysate.
Flow Cytometry
Overlay Peak curve showing Jurkat cells stained with CREB1 recombinant monoclonal antibody, clone 21E3 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human, mouse and rat CREB1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CREB1.
Theoretical MW (kDa)
Calculated MW: 36
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562 whole cell lysate; Lane 2: THP-1 whole cell lysate; Lane 3: Mouse brain tissue lysate; Lane 4: Rat brain tissue lysate.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Jurkat cells stained with CREB1 recombinant monoclonal antibody, clone 21E3 (red line) at 1:50. -
Gene Info — CREB1
Entrez GeneID
1385Protein Accession#
P16220Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
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Interactome
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Pathway
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Disease
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