CREB1 recombinant monoclonal antibody, clone CREBS133-4D11 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of SK-N-MC cells untreated (red) or treated with forskolin (green) using Phospho-CREB (Ser133) (4D11) Rabbit mAb (APC Conjugate), CREBS133-4D11, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells untreated (black) or treated with forskolin (blue). Flow cytometric analysis of SK-N-MC cells secondary antibody only negative control (blue) or untreated (red) or treated with Forskolin (green) using Phospho-CREB (Ser133) APC conjugated antibody CREBS133-4D11.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CREB1.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of SK-N-MC cells untreated (red) or treated with forskolin (green) using Phospho-CREB (Ser133) (4D11) Rabbit mAb (APC Conjugate), CREBS133-4D11, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells untreated (black) or treated with forskolin (blue). Flow cytometric analysis of SK-N-MC cells secondary antibody only negative control (blue) or untreated (red) or treated with Forskolin (green) using Phospho-CREB (Ser133) APC conjugated antibody CREBS133-4D11. -
Gene Info — CREB1
Entrez GeneID
1385Protein Accession#
P16220Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
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Interactome
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Pathway
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Disease
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