FPGS recombinant monoclonal antibody, clone R06-6B1
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: 3T3 lysates with FPGS recombinant monoclonal antibody, clone R06-6B1 (Cat # RAB02274).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FPGS.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FPGS.
Theoretical MW (kDa)
Calculated MW: 65 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: 3T3 lysates with FPGS recombinant monoclonal antibody, clone R06-6B1 (Cat # RAB02274). -
Gene Info — FPGS
Entrez GeneID
2356Protein Accession#
Q05932Gene Name
FPGS
Gene Alias
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Gene Description
folylpolyglutamate synthase
Omim ID
136510Gene Ontology
HyperlinkGene Summary
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022201|OTTHUMP00000022202|folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthetase|tetrahydrofolylpolyglutamate synthase
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Interactome
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Pathway
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Disease
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