FPGS DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FPGS DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRSYGLKTGFFRFGSGSASMGSPSVLSSSPSTSGASTTGWRRPRMAAVSPCPPTSAS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FPGS
Entrez GeneID
2356GeneBank Accession#
BC009901Protein Accession#
no protein_accGene Name
FPGS
Gene Alias
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Gene Description
folylpolyglutamate synthase
Omim ID
136510Gene Ontology
HyperlinkGene Summary
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022201|OTTHUMP00000022202|folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthetase|tetrahydrofolylpolyglutamate synthase
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Interactome
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Pathway
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Disease
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