FPGS polyclonal antibody (A01)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant FPGS.
Immunogen
FPGS (NP_004948, 135 a.a. ~ 232 a.a) partial recombinant protein with GST tag.
Sequence
QVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.89 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Recombinant protein)
ELISA
-
Gene Info — FPGS
Entrez GeneID
2356GeneBank Accession#
NM_004957Protein Accession#
NP_004948Gene Name
FPGS
Gene Alias
-
Gene Description
folylpolyglutamate synthase
Omim ID
136510Gene Ontology
HyperlinkGene Summary
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022201|OTTHUMP00000022202|folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthetase|tetrahydrofolylpolyglutamate synthase
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Folylpoly-ɣ-glutamate synthetase association to the cytoskeleton: Implications to folate metabolon compartmentalization.
Michal Stark, Shachar Raz, Yehuda G Assaraf.
Journal of Proteomics 2021 Mar; 329:104169.
Application:WB-Ce, WB-Tr, Human, CCRF-CEM, HEK 293, HeLa cells.
-
Folylpoly-ɣ-glutamate synthetase association to the cytoskeleton: Implications to folate metabolon compartmentalization.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com