CD8A VHH-hIgG1 humanized monoclonal antibody, clone A9
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Specification
Product Description
Humanized VHH recombinant monoclonal antibody raised against CD8A protein.
Antibody Species
Human
Immunogen
Human CD8A recombinant protein
Reactivity
Human
Specificity
This antibody recognizes human CD8A.
Form
Liquid
Purification
Protein A sepharose
Isotype
Human IgG1 with LALAPG mutations in Fc fragment
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Flow Cytometry
Flow cytometry analysis of enriched human CD3 T cells were treated with CD8A VHH-hIgG1 humanized monoclonal antibody, clone A9 (Cat # RAB01120-M02J). This antibody efficiently bound to human CD8 T cells. -
Gene Info — CD8A
Entrez GeneID
925Gene Name
CD8A
Gene Alias
CD8, Leu2, MAL, p32
Gene Description
CD8a molecule
Gene Ontology
HyperlinkGene Summary
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD8 antigen alpha polypeptide|CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell ant
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Interactome
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Pathway
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