CD8A recombinant monoclonal antibody, clone C8/1779R
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human tonsil with anti-CD8 recombinant monoclonal antibody, clone C8/1779R (Cat # RAB03806).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against recombinant full-length human CD8a protein.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to recombinant full-length human CD8a protein
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Isotype
IgG
Recommend Usage
Flow cytometry (0.5-1 ug/million cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(0.5-1 ug/mL for 30 min at RT)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage Instruction
Store at 2~8°C.
Aliquot to avoid repeated freezing and thawing.Note
Optimal dilutions for each application to be determined by the researcher
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human tonsil with anti-CD8 recombinant monoclonal antibody, clone C8/1779R (Cat # RAB03806).Immunofluorescence
Flow Cytometry
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Gene Info — CD8A
Entrez GeneID
925Protein Accession#
P01732Gene Name
CD8A
Gene Alias
CD8, Leu2, MAL, p32
Gene Description
CD8a molecule
Gene Ontology
HyperlinkGene Summary
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD8 antigen alpha polypeptide|CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell ant
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Interactome
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Pathway
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