EMX2 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EMX2.
Immunogen
A synthetic peptide corresponding to 18 amino acids at internal region of human EMX2.
Host
Rabbit
Reactivity
Human
Specificity
At least two isoforms of EMX2 are known to exist; this antibody will detect both isoforms. EMX2 antibody is predicted to not cross-react with EMX1.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of EMX2 in human lung tissue with EMX2 polyclonal antibody (Cat # PAB25754) at (lane 1) 1 and (lane 2) 2 ug/mL.Immunohistochemistry
Immunohistochemical analysis of EMX2 in human lung tissue with EMX2 polyclonal antibody (Cat # PAB25754) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EMX2
Entrez GeneID
2018Protein Accession#
Q04743Gene Name
EMX2
Gene Alias
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Gene Description
empty spiracles homeobox 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins
Other Designations
OTTHUMP00000020578|empty spiracles homolog 2
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