MMP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with MMP1 polyclonal antibody (Cat # PAB24768).
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MMP1.
Immunogen
A synthetic peptide corresponding to MMP1.
Host
Rabbit
Theoretical MW (kDa)
54
Reactivity
Human
Specificity
MMP1 polyclonal antibody detects endogenous levels of MMP1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with MMP1 polyclonal antibody (Cat # PAB24768).Immunohistochemistry
Immunofluorescence
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Gene Info — MMP1
Entrez GeneID
4312Gene Name
MMP1
Gene Alias
CLG, CLGN
Gene Description
matrix metallopeptidase 1 (interstitial collagenase)
Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq
Other Designations
fibroblast collagenase|interstitial collagenase|matrix metalloprotease 1|matrix metalloproteinase 1|matrix metalloproteinase 1 (interstitial collagenase)
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Interactomes
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Pathways
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Diseases
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Publication Reference
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NF-κB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers.
Poma P, Labbozzetta M, D'Alessandro N, Notarbartolo M.
Amino Acids 2017 Apr; 21(4):225.
Application：WB-Tr, Human, MDA-MB-231, SUM 149, SUM 159 cells.
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NF-κB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers.
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