HEY1 Split FISH Probe
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More Files
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1 Split FISH Probe. Human lung, adenosquamous cell carcinoma showed HEY1 gene split.
Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specifications
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: HEY1(Texas Red)
Size: Approximately 600kb
Fluorophore: Texas Red
Location: 8q21.13Probe 2
Name: HEY1(FITC)
Size: Approximately 650kb
Fluorophore: FITC
Location: 8q21.13Probe Gap
The length of overlap between two probes is approximately 80 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1 Split FISH Probe. Human lung, adenosquamous cell carcinoma showed HEY1 gene split. -
Gene Info — HEY1
Entrez GeneID
23462Gene Name
HEY1
Gene Alias
BHLHb31, CHF2, HERP2, HESR1, HRT-1, MGC1274, OAF1
Gene Description
hairy/enhancer-of-split related with YRPW motif 1
Omim ID
602953Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
HES-related repressor protein 2|basic helix-loop-helix protein OAF1|cardiovascular helix-loop-helix factor 2|hairy-related transcription factor 1
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