HEY1/NCOA2 DY Translocation FISH Probe

Catalog # FT0005

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Size:200 uL
Price: USD $ 2,122.00
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Size:100 uL
Price: USD $ 1,288.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Fluorescent <i>In Situ</i> Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Application

Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

Human hemangiopericytoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human hemangiopericytoma showed no HEY1/NCOA2 DY translocation.

Fluorescent <i>In Situ</i> Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Application

Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

Human mesenchymal chondrosarcoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human mesenchymal chondrosarcoma showed no HEY1/NCOA2 DY translocation.

Fluorescent <i>In Situ</i> Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Application

Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human lung cancer showed no HEY/NCOA2 DY Translocation.

QC Test

Hybridization position of the probes on the chromosome:
Note

Hybridization position of the probes on the chromosome:

Hybridization position of the probes on the chromosome:

  • Specification

    Product Description

    Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology)

    Probe 1

    Name: NCOA2
    Size: Approximately 1300kb
    Fluorophore: Texas Red
    Location: 8q13.3

    Probe 2

    Name: HEY1
    Size: Approximately 1250kb
    Fluorophore: FITC
    Location: 8q21.13

    Probe Gap

    The gap between two probes is approximately 8,200 kb.

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Form

    Liquid

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Storage Instruction

    Store at 4°C in the dark.

    Note

    Hybridization position of the probes on the chromosome:

  • Applications

    Fluorescent In Situ Hybridization (Cell)

    Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

    Human hemangiopericytoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human hemangiopericytoma showed no HEY1/NCOA2 DY translocation.

    Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

    Human mesenchymal chondrosarcoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human mesenchymal chondrosarcoma showed no HEY1/NCOA2 DY translocation.

    Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

    Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human lung cancer showed no HEY/NCOA2 DY Translocation.
  • Gene Info — NCOA2

    Entrez GeneID

    10499

    Gene Name

    NCOA2

    Gene Alias

    GRIP1, KAT13C, MGC138808, NCoA-2, TIF2, bHLHe75

    Gene Description

    nuclear receptor coactivator 2

    Omim ID

    601993

    Gene Ontology

    Hyperlink

    Other Designations

    glucocorticoid receptor-interacting protein-1

  • Gene Info — HEY1

    Entrez GeneID

    23462

    Gene Name

    HEY1

    Gene Alias

    BHLHb31, CHF2, HERP2, HESR1, HRT-1, MGC1274, OAF1

    Gene Description

    hairy/enhancer-of-split related with YRPW motif 1

    Omim ID

    602953

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq

    Other Designations

    HES-related repressor protein 2|basic helix-loop-helix protein OAF1|cardiovascular helix-loop-helix factor 2|hairy-related transcription factor 1

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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