FPGS recombinant monoclonal antibody, clone 30C11
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FPGS.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FPGS.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing HepG2 cells stained with FPGS recombinant monoclonal antibody, clone 30C11 (red line) at 1:50. -
Gene Info — FPGS
Entrez GeneID
2356Protein Accession#
Q05932Gene Name
FPGS
Gene Alias
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Gene Description
folylpolyglutamate synthase
Omim ID
136510Gene Ontology
HyperlinkGene Summary
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022201|OTTHUMP00000022202|folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthetase|tetrahydrofolylpolyglutamate synthase
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