BMP7 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human BMP7 full-length ORF ( AAH08584, 1 a.a. - 431 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
73.15
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BMP7
Entrez GeneID
655GeneBank Accession#
BC008584Protein Accession#
AAH08584Gene Name
BMP7
Gene Alias
OP-1
Gene Description
bone morphogenetic protein 7
Omim ID
112267Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000031357|osteogenic protein 1
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Gremlin-Mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis.
Myllarniemi M, Lindholm P, Ryynanen MJ, Kliment CR, Salmenkivi K, Keski-Oja J, Kinnula VL, Oury TD, Koli K.
American Journal of Respiratory and Critical Care Medicine 2007 Nov; 177(3):321.
Application：Func, Mouse, Mouse bronchoalveolar lavage, lung.
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Gremlin-Mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis.
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