BMP7 (Human) Recombinant Protein
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Specifications
Product Description
Human BMP7 (P18075) recombinant protein expressed in HEK293 cells.
Sequence
DFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKAT.
Host
Human
Theoretical MW (kDa)
30-38
Form
Lyophilized
Preparation Method
HEK 293T cell expression system
Purity
> 95% by SDS-PAGE
Activity
The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) and is typically 50-250 ng/mL.
Storage Buffer
The BMP7 was lyophilized from 1mg/mL in 1xPBS.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — BMP7
Entrez GeneID
655Protein Accession#
P18075Gene Name
BMP7
Gene Alias
OP-1
Gene Description
bone morphogenetic protein 7
Omim ID
112267Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000031357|osteogenic protein 1
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Interactomes
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