BMP7 (Human) Recombinant Protein
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Specification
Product Description
Human BMP7 (P18075) recombinant protein with His-tag at N-terminal expressed in Nicotiana benthamiana expression system.
Sequence
HHHHHHSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSVILKKYRNMVVRACGCH.
Host
Nicotiana benthamiana
Theoretical MW (kDa)
16.5
Form
Lyophilized
Preparation Method
Nicotiana benthamiana expression system
Purity
> 97% by SDS-PAGE
Activity
The biological activity of BMP-7 was measured by the ability to induce alkaline phosphatase production by ATDC5 cells, ED50 is less than 40 ng/mL, corresponding to a specific activity of 25,000 units/mg.
Storage Buffer
BMP-7 was lyophilized from a solution containing Tris-HCl 0.05M buffer at pH 7.4.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — BMP7
Entrez GeneID
655Protein Accession#
P18075Gene Name
BMP7
Gene Alias
OP-1
Gene Description
bone morphogenetic protein 7
Omim ID
112267Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000031357|osteogenic protein 1
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