BAX recombinant monoclonal antibody, clone 15D9
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More Files
- More Functions
Immunohistochemistry
Immunohistochemistry image of BAX recombinant monoclonal antibody, clone 15D9 diluted at 1:50 and staining in paraffin-embedded human rectal cancer performed on a Leica BondTM system.
Flow Cytometry
Overlay Peak curve showing Hela cells stained with BAX recombinant monoclonal antibody, clone 15D9 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human BAX.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human BAX.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of BAX recombinant monoclonal antibody, clone 15D9 diluted at 1:50 and staining in paraffin-embedded human rectal cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Hela cells stained with BAX recombinant monoclonal antibody, clone 15D9 (red line) at 1:50. -
Gene Info — BAX
Entrez GeneID
581Protein Accession#
Q07812Gene Name
BAX
Gene Alias
BCL2L4
Gene Description
BCL2-associated X protein
Omim ID
600040Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
Other Designations
apoptosis regulator BAX
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Interactome
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Pathway
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Disease
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