CHRM3 recombinant monoclonal antibody, clone 2D4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CHRM3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human CHRM3.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: PC3 whole cell lysate.Immunohistochemistry
Immunohistochemistry image of CHRM3 recombinant monoclonal antibody, clone 2D4 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CHRM3
Entrez GeneID
1131Protein Accession#
P20309Gene Name
CHRM3
Gene Alias
HM3
Gene Description
cholinergic receptor, muscarinic 3
Omim ID
118494Gene Ontology
HyperlinkGene Summary
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq
Other Designations
m3 muscarinic receptor|muscarinic acetylcholine receptor M3
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Interactome
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Pathway
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Disease
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