TNFRSF9 recombinant monoclonal antibody, clone 4B4-1-1
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human TNFRSF9.
Antibody Species
Mouse
Immunogen
Original antibody is raised against a fusion protein of human TNFRSF9 antigen and glutathione s transferase (GST).
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Concentration
batch dependent
Isotype
IgG1 kappa
Recommend Usage
Blocking
ELISA
Flow Cytometry
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Blocking
Flow Cytometry
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Gene Info — TNFRSF9
Entrez GeneID
3604Gene Name
TNFRSF9
Gene Alias
4-1BB, CD137, CDw137, ILA, MGC2172
Gene Description
tumor necrosis factor receptor superfamily, member 9
Omim ID
602250Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq
Other Designations
4-1BB ligand receptor|CD137 antigen|OTTHUMP00000001360|OTTHUMP00000044294|T cell antigen ILA|homolog of mouse 4-1BB|induced by lymphocyte activation (ILA)|interleukin-activated receptor, homolog of mouse Ly63|receptor protein 4-1BB
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Interactome
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Pathway
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Disease
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