GSN recombinant monoclonal antibody, clone R06-4B4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human GSN.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human GSN.
Theoretical MW (kDa)
Calculated MW: 86 kD
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: MCF-7 and Lane 2: 3T3 lysates with GSN recombinant monoclonal antibody, clone R06-4B4 (Cat # RAB02259).Immunohistochemistry
Immunofluorescence
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Gene Info — GSN
Entrez GeneID
2934Protein Accession#
P06396Gene Name
GSN
Gene Alias
DKFZp313L0718
Gene Description
gelsolin (amyloidosis, Finnish type)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022011|OTTHUMP00000162202|gelsolin
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Interactome
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Pathway
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Disease
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