IL18 recombinant monoclonal antibody, clone R02-8B2
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IL18.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human IL18.
Theoretical MW (kDa)
Calculated MW: 22 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Hela lysates with IL18 recombinant monoclonal antibody, clone R02-8B2 (Cat # RAB02175).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon cancer with IL18 recombinant monoclonal antibody, clone R02-8B2 (Cat # RAB02175). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Gene Info — IL18
Entrez GeneID
3606Protein Accession#
Q14116Gene Name
IL18
Gene Alias
IGIF, IL-18, IL-1g, IL1F4, MGC12320
Gene Description
interleukin 18 (interferon-gamma-inducing factor)
Omim ID
600953Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. [provided by RefSeq
Other Designations
IL-1 gamma|interferon-gamma-inducing factor|interleukin 18|interleukin-1 gamma|interleukin-18
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Interactome
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