NPPA polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NPPA.
Immunogen
A synthetic peptide corresponding to amino acids 104-123 of human NPPA.
Host
Rabbit
Reactivity
Human, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500)
Immunoprecipitation (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunoprecipitation
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Gene Info — NPPA
Entrez GeneID
4878Gene Name
NPPA
Gene Alias
ANF, ANP, ATFB6, CDD-ANF, PND
Gene Description
natriuretic peptide precursor A
Omim ID
108780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
Other Designations
OTTHUMP00000002504|OTTHUMP00000044485|atrial natriuretic peptide|natriuretic peptide precursor A variant 2|pronatriodilatin
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients.
Ursula Hoffmann, Martina Brueckmann, Thomas Bertsch, Mike Wiessner, Claudia Liebetrau, Siegfried Lang, Karl K Haase, Martin Borggrefe, Guenter Huhle.
Clinical Laboratory 2005 Jan; 51(7-8):373.
Application:ELISA, Human, Human plasma.
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Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients.
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