NPPA rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NPPA peptide using ARM Technology.
Immunogen
A synthetic peptide of human NPPA is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NPPA peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NPPA
Entrez GeneID
4878GeneBank Accession#
NPPAGene Name
NPPA
Gene Alias
ANF, ANP, ATFB6, CDD-ANF, PND
Gene Description
natriuretic peptide precursor A
Omim ID
108780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
Other Designations
OTTHUMP00000002504|OTTHUMP00000044485|atrial natriuretic peptide|natriuretic peptide precursor A variant 2|pronatriodilatin
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