NPPA monoclonal antibody, clone ADHD-14
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human NPPA.
Immunogen
A synthetic peptide corresponding to human NPPA.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human NPPA, in native form and recombinant. Superfamily members of NPPA are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PC-3 cell lysate.Immunoprecipitation
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Gene Info — NPPA
Entrez GeneID
4878Protein Accession#
P01160Gene Name
NPPA
Gene Alias
ANF, ANP, ATFB6, CDD-ANF, PND
Gene Description
natriuretic peptide precursor A
Omim ID
108780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
Other Designations
OTTHUMP00000002504|OTTHUMP00000044485|atrial natriuretic peptide|natriuretic peptide precursor A variant 2|pronatriodilatin
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Interactome
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Pathway
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Disease
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