NAT1 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of NAT1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human NAT1.
Sequence
C-HSDLLEDSKYRKIY
Host
Goat
Theoretical MW (kDa)
33.9
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — NAT1
Entrez GeneID
9Protein Accession#
NP_000653.3Gene Name
NAT1
Gene Alias
AAC1, NATI
Gene Description
N-acetyltransferase 1 (arylamine N-acetyltransferase)
Omim ID
108345Gene Ontology
HyperlinkGene Summary
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
N-acetyltransferase 1|OTTHUMP00000122488|arylamide acetylase 1 (N-acetyltransferase 1)|arylamine N-acetyltransferase 1
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Interactomes
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Pathways
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Diseases
- Abnormalities
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer disease
- Amnesia
- Asthma
- Breast cancer
- Breast Neoplasms
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Publication Reference
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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos.
Smelt VA, Upton A, Adjaye J, Payton MA, Boukouvala S, Johnson N, Mardon HJ, Sim E.
Human Molecular Genetics 2000 Apr; 9(7):1101.
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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos.
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