NAT1 rabbit monoclonal antibody
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Specifications
Product Description
Rabbit monoclonal antibody raised against a human NAT1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NAT1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NAT1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NAT1
Entrez GeneID
9GeneBank Accession#
NAT1Gene Name
NAT1
Gene Alias
AAC1, NATI
Gene Description
N-acetyltransferase 1 (arylamine N-acetyltransferase)
Omim ID
108345Gene Ontology
HyperlinkGene Summary
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
N-acetyltransferase 1|OTTHUMP00000122488|arylamide acetylase 1 (N-acetyltransferase 1)|arylamine N-acetyltransferase 1
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Interactomes
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Pathways
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Diseases
- Abnormalities
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer disease
- Amnesia
- Asthma
- Breast cancer
- Breast Neoplasms
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