SORT1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Frozen sections)
IHC on rat spinal cord (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
Immunohistochemistry (Frozen sections)
IHC on rat DRG (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
Immunohistochemistry (Frozen sections)
IHC on rat trigeminal nerve (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant SORT1.
Immunogen
Recombinant protein corresponding to extracellular region of human SORT1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Frozen sections)
IHC on rat spinal cord (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.Immunohistochemistry (Frozen sections)
IHC on rat DRG (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.Immunohistochemistry (Frozen sections)
IHC on rat trigeminal nerve (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SORT1
Entrez GeneID
6272Protein Accession#
Q99523Gene Name
SORT1
Gene Alias
Gp95, NT3
Gene Description
sortilin 1
Omim ID
602458Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq
Other Designations
OTTHUMP00000013784|neurotensin receptor 3
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Interactome
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Pathway
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Disease
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