TNFRSF10A (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Enzyme-linked Immunoabsorbent Assay
Immobilized Human TRAIL, No Tag at 2ug/mL (100uL/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 51.6ng/mL determined by ELISA.
SEC-HPLC
The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human TRAIL R1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
-
Specification
Product Description
Human TNFRSF10A (O00220, Pro34-Asn239) partial recombinant protein with hFc tag at C-Terminus expressed in HEK293 cells.
Sequence
Pro34-Asn239
Host
Human
Theoretical MW (kDa)
48.8
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human TRAIL R1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
-
Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human TRAIL, No Tag at 2ug/mL (100uL/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 51.6ng/mL determined by ELISA.Functional Study
SDS-PAGE
-
Gene Info — TNFRSF10A
Entrez GeneID
8797Protein Accession#
O00220Gene Name
TNFRSF10A
Gene Alias
APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Gene Description
tumor necrosis factor receptor superfamily, member 10a
Omim ID
603611Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq
Other Designations
TNF-related apoptosis inducing ligand receptor 1|cytotoxic TRAIL receptor|death receptor 4
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com