IL25 (Human) Recombinant Protein
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Specification
Product Description
Human IL25 (Q9H293, 33 a.a. - 177 a.a.) partial recombinant protein with His-tag at C-terminus expressed in HEK293 cells.
Sequence
DGSYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMGHHHHHH
Host
Mammals
Theoretical MW (kDa)
17.8
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% by SDS-PAGE
Activity
Measured by the binding ability in a functional ELISA with Human IL-17 RB.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS pH 7.4 (20% glycerol)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL25
Entrez GeneID
64806Protein Accession#
Q9H293Gene Name
IL25
Gene Alias
IL-17E, IL-25, IL17E
Gene Description
interleukin 25
Omim ID
605658Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. This cytokine can induce NF-kappaB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17BR. Studies of the similar gene in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
interleukin 17E
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Interactome
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Pathway
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