BMP2 (Human) Recombinant Protein
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Specification
Product Description
Human BMP2 (P12643, 283 a.a. - 396 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Host
Escherichia coli
Theoretical MW (kDa)
26
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by gel clotting method)
Activity
The ED50 as determined by the ability to induce alkaline phosphatase production by ATDC-5 Cells is 0.07 - 0.2 ug/ml. The ED50 as determined by the ability to induce alkaline phosphatase production by C2C12 cells is 0.2 - 1 ug/ml
Quality Control Testing
2 ug protein in Reducing and Non-Reducing SDS PAGE Stained with Coomassie Blue
Storage Buffer
Lyophilized from 20 mM AcOH or 5 mM HClr up to 100 ug/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — BMP2
Entrez GeneID
650Protein Accession#
P12643Gene Name
BMP2
Gene Alias
BMP2A
Gene Description
bone morphogenetic protein 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq
Other Designations
OTTHUMP00000030228
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Interactome
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