GDNF monoclonal antibody, clone ABDB-7
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GDNF monoclonal antibody, clone ABDB-7 (Cat # MAB20084).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human GDNF.
Immunogen
A synthetic peptide corresponding to human GDNF.
Host
Rabbit
Theoretical MW (kDa)
23.72
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GDNF monoclonal antibody, clone ABDB-7 (Cat # MAB20084).Flow Cytometry
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Gene Info — GDNF
Entrez GeneID
2668Protein Accession#
P39905Gene Name
GDNF
Gene Alias
ATF1, ATF2, HFB1-GDNF
Gene Description
glial cell derived neurotrophic factor
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
Other Designations
astrocyte-derived trophic factor|glial cell line derived neurotrophic factor|glial derived neurotrophic factor
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Interactome
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Disease
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