HDAC1 monoclonal antibody, clone CL0510
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with HDAC1 monoclonal antibody, clone CL0510 (Cat # MAB15637).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with HDAC1 monoclonal antibody, clone CL0510 (Cat # MAB15637) shows strong nuclear immunoreactivity in the seminiferous ducts.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human HDAC1.
Immunogen
Recombinant protein corresponding to human HDAC1.
Epitope
This antibody binds to an epitope located within the peptide sequence EGGRKNSSNFKKAKR as determined by overlapping synthetic peptides.
Sequence
RIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKE
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with HDAC1 monoclonal antibody, clone CL0510 (Cat # MAB15637).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with HDAC1 monoclonal antibody, clone CL0510 (Cat # MAB15637) shows strong nuclear immunoreactivity in the seminiferous ducts. -
Gene Info — HDAC1
Entrez GeneID
3065Protein Accession#
Q13547Gene Name
HDAC1
Gene Alias
DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
Gene Description
histone deacetylase 1
Omim ID
601241Gene Ontology
HyperlinkGene Summary
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq
Other Designations
OTTHUMP00000008745|reduced potassium dependency, yeast homolog-like 1
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Interactome
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Pathway
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Disease
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