VIM DNAxPab
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a partial-length human VIM DNA using DNAx™ Immune technology.
Technology
Immunogen
VIM (NP_003371.2, 207 a.a. ~ 226 a.a) partial-length human DNA
Sequence
RQDVDNASLARLDLERKVES
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of VIM expression in transfected 293T cell line by VIM DNAxPab polyclonal antibody.
Lane 1: VIM transfected lysate(23.32 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — VIM
Entrez GeneID
7431GeneBank Accession#
NM_003380.2Protein Accession#
NP_003371.2Gene Name
VIM
Gene Alias
FLJ36605
Gene Description
vimentin
Omim ID
193060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
Other Designations
OTTHUMP00000019224
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