GCDH MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GCDH protein.
Immunogen
GCDH (NP_000150.1, 1 a.a. ~ 438 a.a) full-length human protein.
Sequence
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTASK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
GCDH MaxPab polyclonal antibody. Western Blot analysis of GCDH expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of GCDH expression in transfected 293T cell line (H00002639-T01) by GCDH MaxPab polyclonal antibody.
Lane 1: GCDH transfected lysate(48.18 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to GCDH on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — GCDH
Entrez GeneID
2639GeneBank Accession#
NM_000159.2Protein Accession#
NP_000150.1Gene Name
GCDH
Gene Alias
ACAD5, GCD
Gene Description
glutaryl-Coenzyme A dehydrogenase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
glutaryl-CoA dehydrogenase, mitochondrial
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Interactome
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Pathway
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Disease
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