GCDH polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human GCDH.
Immunogen
A synthetic peptide corresponding to C-terminus of human GCDH.
Sequence
IARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITG
Host
Rabbit
Theoretical MW (kDa)
48
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GCDH polyclonal antibody (Cat # PAB30097) at 2.5 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human muscle with GCDH polyclonal antibody (Cat # PAB30097) at 4-8 ug/mL working concentration. -
Gene Info — GCDH
Entrez GeneID
2639GeneBank Accession#
NM_000159Protein Accession#
NP_000150;Q92947Gene Name
GCDH
Gene Alias
ACAD5, GCD
Gene Description
glutaryl-Coenzyme A dehydrogenase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
glutaryl-CoA dehydrogenase, mitochondrial
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Interactome
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Pathway
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Disease
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