AHCY monoclonal antibody (M09), clone M2

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Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant AHCY.
Immunogen
AHCY (AAH11606, 1 a.a. ~ 432 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKHPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (73.26 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
AHCY monoclonal antibody (M09), clone M2. Western Blot analysis of AHCY expression in A-549 ( Cat # L025V1 ).Western Blot (Cell lysate)
AHCY monoclonal antibody (M09), clone M2. Western Blot analysis of AHCY expression in different cell lines.Western Blot (Recombinant protein)
ELISA
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Gene Info — AHCY
Entrez GeneID
191GeneBank Accession#
BC011606Protein Accession#
AAH11606Gene Name
AHCY
Gene Alias
SAHH
Gene Description
S-adenosylhomocysteine hydrolase
Omim ID
180960Gene Ontology
HyperlinkGene Summary
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000030684|adenosylhomocysteinase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer.
Kim HJ, Kang HJ, Lee H, Lee ST, Yu MH, Kim H, Lee C.
Journal of Proteome Research 2009 Mar; 8(3):1368.
Application:WB-Ce, WB-Ti, Human, Human colorectal cancer, Colo201, Colo205, DLD-1, HCT-8, HCT-116, HT-29, LOVO, RKO, SNUC2A, SNUC4, WIDR cells.
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Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer.
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