IGH Split FISH Probe

Catalog # FS0069





Size:200 uL
Price: USD $ 2,122.00
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Size:100 uL
Price: USD $ 1,288.00
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Contact Info
  • +1-909-264-1399
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
QC Test

  • Specification

    Product Description

    Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).

    Probe 1

    Name: IGH
    Size: Approximately 220kb
    Fluorophore: Texas Red
    Location: 14q32

    Probe 2

    Name: IGH
    Size: Approximately 900kb
    Fluorophore: FITC
    Location: 14q32




    Genomic DNA






    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Probe Position

    Storage Instruction

    Store at 4°C in the dark.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

  • Gene Info — IGH

    Entrez GeneID


    Gene Name


    Gene Alias

    IGH, IGH.1@, IGHDY1, MGC72071, MGC88774

    Gene Description

    immunoglobulin heavy locus

    Gene Ontology


    Gene Summary

    Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. This region represents the germline organization of the heavy chain locus. The locus includes V (variable), D (diversity), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single D segment with a J segment; this partially rearranged D-J gene is then joined to a V segment. The rearranged V-D-J is then transcribed with the IGHM constant region; this transcript encodes a mu heavy chain. Later in development B cells generate V-D-J-Cmu-Cdelta pre-messenger RNA, which is alternatively spliced to encode either a mu or a delta heavy chain. Mature B cells in the lymph nodes undergo switch recombination, so that the V-D-J gene is brought in proximity to one of the IGHG, IGHA, or IGHE genes and each cell expresses either the gamma, alpha, or epsilon heavy chain. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V, D, J, and C segments are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq

    Other Designations


  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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