PRDM16 FISH Probe

Catalog # FA0003

Size

Price

Stock

Quantity

Size:200 uL
Price: USD $ 2,585.00
Stock:
made to order, 3 weeks
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 250 uL

    Storage Instruction

    Store at 4°C in the dark.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

  • Gene Info — PRDM16

    Entrez GeneID

    63976

    Gene Name

    PRDM16

    Gene Alias

    KIAA1675, MEL1, MGC166915, PFM13

    Gene Description

    PR domain containing 16

    Omim ID

    605557

    Gene Ontology

    Hyperlink

    Gene Summary

    The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

    Other Designations

    MDS1/EVI1-like|PR-domain zinc finger protein 16|transcription factor MEL1

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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