Products

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged SSX4 is 0.1 ng/ml as a capture antibody.

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged SSX4 is 0.03 ng/ml as a capture antibody.

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged SSX4 is approximately 3ng/ml as a capture antibody.

ELISA

Immunofluorescence

Immunofluorescence of monoclonal antibody to SSX4 on HeLa cell . [antibody concentration 10 ug/ml]

Entrez GeneID

6759

GeneBank Accession#

NM_005636

Protein Accession#

NP_005627

Gene Name

SSX4

Gene Alias

MGC119056, MGC12411

Gene Description

synovial sarcoma, X breakpoint 4

Omim ID

300326

Gene Ontology

Hyperlink

Gene Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Other Designations

OTTHUMP00000024292