SYN1 (phospho S9) monoclonal antibody, clone FCE-19
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of (1) Human brain lysate, (2) Human brain lysate treated with AP using SYN1 (phospho S9) monoclonal antibody, clone FCE-19.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SYN1.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S9 of human SYN1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.4-0.5 mg/mL BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of (1) Human brain lysate, (2) Human brain lysate treated with AP using SYN1 (phospho S9) monoclonal antibody, clone FCE-19.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — SYN1
Entrez GeneID
6853Protein Accession#
P17600Gene Name
SYN1
Gene Alias
SYN1a, SYN1b, SYNI
Gene Description
synapsin I
Gene Ontology
HyperlinkGene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000023229|OTTHUMP00000023230|brain protein 4.1
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Interactome
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Disease
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