SYN1 monoclonal antibody (M06), clone 4F6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SYN1.
Immunogen
SYN1 (NP_008881, 362 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (96)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SYN1 monoclonal antibody (M06), clone 4F6. Western Blot analysis of SYN1 expression in A-431 ( Cat # L015V1 ).Western Blot (Cell lysate)
SYN1 monoclonal antibody (M06), clone 4F6 Western Blot analysis of SYN1 expression in MCF-7 ( Cat # L046V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — SYN1
Entrez GeneID
6853GeneBank Accession#
NM_006950Protein Accession#
NP_008881Gene Name
SYN1
Gene Alias
SYN1a, SYN1b, SYNI
Gene Description
synapsin I
Gene Ontology
HyperlinkGene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000023229|OTTHUMP00000023230|brain protein 4.1
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Interactome
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Disease
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