EXOSC1 monoclonal antibody (M01), clone 2E9
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant EXOSC1.
Immunogen
EXOSC1 (AAH22067, 1 a.a. ~ 195 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (47.19 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of EXOSC1 expression in transfected 293T cell line by EXOSC1 monoclonal antibody (M01), clone 2E9.
Lane 1: EXOSC1 transfected lysate (Predicted MW: 21.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EXOSC1 is 3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to EXOSC1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — EXOSC1
Entrez GeneID
51013GeneBank Accession#
BC022067Protein Accession#
AAH22067Gene Name
EXOSC1
Gene Alias
CGI-108, CSL4, Csl4p, SKI4, Ski4p, hCsl4p, p13
Gene Description
exosome component 1
Omim ID
606493Gene Ontology
HyperlinkGene Summary
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq
Other Designations
3'-5' exoribonuclease CSL4 homolog|CSL4 exosomal core protein homolog|OTTHUMP00000020203|exosomal core protein CSL4|homolog of yeast exosomal core protein CSL4
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Interactomes
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Pathways
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