CD28 monoclonal antibody (M22), clone 4B5
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant CD28.
Immunogen
CD28 (NP_006130.1, 18 a.a. ~ 152 a.a) partial recombinant protein.
Sequence
GNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (17.05 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CD28
Entrez GeneID
940GeneBank Accession#
NM_006139.3Protein Accession#
NP_006130.1Gene Name
CD28
Gene Alias
MGC138290, Tp44
Gene Description
CD28 molecule
Omim ID
186760Gene Ontology
HyperlinkGene Summary
CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
Other Designations
CD28 antigen|CD28 antigen (Tp44)|T-cell-specific surface glycoprotein
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Interactomes
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Pathways
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Diseases
- Acute Disease
- Arthritis
- Asthma
- Behcet Syndrome
- Bronchiolitis
- Carcinoma
- Celiac Disease
- Cholangitis
- Colon cancer
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