CD28 scFv-hIgG1 humanized monoclonal antibody
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Specification
Product Description
Humanized scFv recombinant monoclonal antibody raised against CD28.
Antibody Species
Human
Immunogen
Human CD28 recombinant protein
Reactivity
Human
Specificity
CD28
Form
Liquid
Purification
Protein A sepharose
Isotype
Human IgG1 with LALAPG mutations in Fc fragment
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Flow Cytometry
Flow cytometric analysis verified the effective binding of CD28 scFv-hIgG1 humanized monoclonal antibody (Cat # RAB07810-M01J) to activated human CD3 T cells. -
Gene Info — CD28
Entrez GeneID
940Gene Name
CD28
Gene Alias
MGC138290, Tp44
Gene Description
CD28 molecule
Omim ID
186760Gene Ontology
HyperlinkGene Summary
CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
Other Designations
CD28 antigen|CD28 antigen (Tp44)|T-cell-specific surface glycoprotein
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Interactome
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Pathway
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Disease
- Acute Disease
- Arthritis
- Asthma
- Behcet Syndrome
- Bronchiolitis
- Carcinoma
- Celiac Disease
- Cholangitis
- Colon cancer
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