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Last updated: 2015/3/22
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CYP19A1 polyclonal antibody

  • Catalog # : PAB12453
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP19A1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 400-502 of human CYP19A1.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Horse, Human, Primates, Rabbit
  • Specificity:
  • This antibody is specific to aromatase.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.1% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of CYP19A1 in human fetal temporal lobe lysate using CYP19A1 polyclonal antibody (Cat # PAB12453). ECL exposure, 1-2 minutes.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1588
  • Gene Name:
  • CYP19A1
  • Gene Alias:
  • ARO,ARO1,CPV1,CYAR,CYP19,MGC104309,P-450AROM
  • Gene Description:
  • cytochrome P450, family 19, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162543,aromatase,cytochrome P450, family 19,cytochrome P450, subfamily XIX (aromatization of androgens),estrogen synthetase,flavoprotein-linked monooxygenase,microsomal monooxygenase
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