ADAMTS8 monoclonal antibody (M01), clone 5A3
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAMTS8 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADAMTS8.
Immunogen
ADAMTS8 (NP_008968, 781 a.a. ~ 890 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (84)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAMTS8 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — ADAMTS8
Entrez GeneID
11095GeneBank Accession#
NM_007037Protein Accession#
NP_008968Gene Name
ADAMTS8
Gene Alias
ADAM-TS8, FLJ41712, METH2
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 8
Omim ID
605175Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
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Publication Reference
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EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS.
George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
United States Patent Application Publication 2010 Feb; [Epub].
Application：Array, Mammal, Prostate cancer.
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EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS.
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