AATK monoclonal antibody (M03), clone 5B8
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant AATK.
Immunogen
AATK (AAH47378, 161 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SPEFVLKEAQEGCEPQAFAELASEGEGPGPETRLSTSLSGLNEKNPYRDSAYFSDLEAEAEATSGPEKKCGGDRAPGPELGLRSTGQPSEQVCLRPGVSG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (61); Rat (59)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
AATK monoclonal antibody (M03), clone 5B8 Western Blot analysis of AATK expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to AATK on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AATK is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — AATK
Entrez GeneID
9625GeneBank Accession#
BC047378Protein Accession#
AAH47378Gene Name
AATK
Gene Alias
AATYK, AATYK1, KIAA0641, LMR1, LMTK1, p35BP
Gene Description
apoptosis-associated tyrosine kinase
Omim ID
605276Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. [provided by RefSeq
Other Designations
CDK5-binding protein|lemur tyrosine kinase 1|p35-binding protein|serine/threonine-protein kinase LMTK1
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